Science and Engineering Associate 2 (1 Year Fixed-Term)

DESIRED QUALIFICATIONS:

•    Master's degree in molecular biology, genetics, bioengineering, or related field preferred
•    2+ years experience with CRISPR-based genetic screening technologies
•    Demonstrated experience with viral vector production (lentivirus and AAV) including concentration and titration
•    Proficiency in molecular cloning techniques (Gibson assembly, Golden Gate cloning, traditional restriction cloning)
•    Experience with flow cytometry and FACS sorting for cell isolation
•    Hands-on experience with single-cell genomics platforms, particularly 10X Genomics (Flex, Gene Expression)
•    Experience with mammalian cell culture and sterile technique
•    Familiarity with next-generation sequencing library preparation and quality control
•    Basic bioinformatics skills for analyzing pooled screening data (R or Python preferred)
•    Experience managing complex multi-stakeholder research projects
•    Demonstrated ability to work independently while contributing to collaborative team environment
•    Strong written and verbal communication skills for interfacing with collaborators
•    Experience with project management and tracking deliverables/milestones

EDUCATION & EXPERIENCE (REQUIRED):

Bachelor’s degree in engineering, science, or related field and three years of relevant experience; or a combination of education and relevant experience.

KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):

•    Demonstrated knowledge and skills of advanced scientific or engineering principles and practices. 
•    Demonstrated experience applying complex scientific and engineering principles and performing special technical services involving both development and performance. 
•    In-depth experience with software applications, systems, or programs relevant for the job. 
•    Ability to independently oversee and manage instrumentation or system installation. 
•    Ability to collaborate with senior engineering and scientific staff to design and develop special purpose equipment and/or systems. 
•    Experience overseeing the plan, design, and implementation of major scientific or engineering initiatives and ensuring project objective are met. 
•    Demonstrated ability to review research proposals, evaluate research capabilities, and make recommendations. 
•    Demonstrated ability to establish, communicate, and enforce compliance with health and safety policies and procedures. 
•    Experience overseeing a laboratory space or unit and supervising the work of technicians and other staff associated with the group.
•    Demonstrated ability to effectively supervise and train a diverse work staff. 

CERTIFICATIONS & LICENSES:

None

PHYSICAL REQUIREMENTS*:

•    Frequently grasp lightly/fine manipulation, perform desk-based computer tasks, lift/carry/push/pull objects that weigh up to 10 pounds.
•    Occasionally stand/walk, sit, twist/bend/stoop/squat, grasp forcefully.
•    Rarely kneel/crawl, climb (ladders, scaffolds, or other), reach/work above shoulders, use a telephone, writing by hand, sort/file paperwork or parts, operate foot and/or hand controls, lift/carry/push/pull objects that weigh >40 pounds.

* - Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

Additional PHYSICAL REQUIREMENTS: 

•    Extended periods of standing while performing bench work (4-6 hours)
•    Fine motor skills for pipetting and microscopy work
•    Ability to work in biosafety cabinet for extended periods

WORKING CONDITIONS:

•    May be exposed to high voltage electricity, radiation or electromagnetic fields, lasers, noise > 80dB TWA, Allergens/Biohazards/Chemicals /Asbestos, confined spaces, working at heights ?10 feet, temperature extremes, heavy metals, unusual work hours or routine overtime and/or inclement weather. 
•    May require travel.

Additional WORKING CONDITIONS: 

•    Work with biological materials including viral vectors requiring BSL-2/BSL-2+ containment
•    Exposure to cell culture media and biological specimens
•    Work with UV light sources and fluorescent microscopy equipment
•    Occasional weekend or evening work required for time-sensitive experiments