Stanford School of Medicine is
seeking a cryo-EM scientist to support the operation of our expanding,
state-of-the-art electron microscopy facility. The facility includes 2 Titan Krios
and 1 Tecnai F20 microscopes for single particle and tomography studies. This
team member, along with others, will be responsible for oversight and
maintenance of these microscopes as well as training and assisting users. The
cryo-EM specialist will have ample opportunities to advance and grow
professionally within our research environment, which includes the scientific
communities at both Stanford and SLAC.
We are looking for a colleague who
will be excited about interacting with researchers at all levels and will
consistently strive to maintain a state-of-the-art facility. This EM scientist
will join a team of two others to support our new cryo-EM initiative. This job
is an excellent opportunity for an electron microscopist interested in joining
the Stanford/SLAC community.
Duties
include:
Interface and
collaborate with High Performance Computing team, who will assist with
computational needs for optimal data
collection, storage and data processing.
Interface and
collaborate with Microscopy Core, which houses electron microscopes for
preliminary screening of samples Maintain FEI Tecnai F20 and Krios microscopes.
This duty requires interfacing with FEI engineers to ensure optimal performance
of the microscopes.
Maintain
ancillary, cryo-EM related equipment such as Vitrobot, glow discharger etc.
Load samples and
tune microscopes prior to data collection.
Train and oversee
users for data collection.
Evaluate quality
of data obtained by users.
Implement data
collection strategies that will benefit our user community.
Maintain accurate
logs for microscope performance and usage.
* - Other duties may also be assigned
DESIRED
QUALIFICATIONS:
Ph.D.
in same field with 2 years of cryo-EM experience
BA or
MA in structural biology, biochemistry, bioengineering or related field
plus 5 years of related experience; or At least 2-5 years of cryo-EM
experience, with expertise in handling samples, using microscopes and
evaluating data.
Excellent
communication and interpersonal skills.
Solid
understanding of the principles of transmission electron microscopy.
Best
practice knowledge of computational image processing and analysis of
cryo-EM images.
General
understanding of single particle cryo-EM workflow; experience in cryo
electron tomography is a plus.
EDUCATION
& EXPERIENCE (REQUIRED):
Associate
degree or certificate of completion in a related engineering or related scientific
discipline, or three to four years of equivalent work experience.
KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):
Experience
applying scientific and engineering principles and practices to perform
technical services and support.
Experience with
data analysis, experimental process, design, and development of prototypes,
equipment, and/or systems related to area of specialization.
Ability to write
clear documentation, perform administrative duties, and research protocol
maintenance related to research studies and/or scientific/engineering projects.
Experience with
software applications, systems, or programs relevant for the job.
Ability to
interpret and determine validity of data and check own work.
Ability to
communicate, liaise, and work with staff, students, faculty, and outside
vendors.
Ability
to effectively supervise and train a diverse work staff.
CERTIFICATIONS
& LICENSES:
None
PHYSICAL REQUIREMENTS*:
Frequently grasp
lightly/fine manipulation, perform desk-based computer tasks, lift/carry/push/pull
objects that weigh up to 10 pounds.
Occasionally
stand/walk, sit, twist/bend/stoop/squat, grasp forcefully.
Rarely
kneel/crawl, climb (ladders, scaffolds, or other), reach/work above shoulders,
use a telephone, writing by hand, sort/file paperwork or parts, operate foot
and/or hand controls, lift/carry/push/pull objects that weigh >40 pounds.
* - Consistent with its obligations
under the law, the University will provide reasonable accommodation to any
employee with a disability who requires accommodation to perform the essential
functions of his or her job.
WORKING
CONDITIONS:
May be exposed to high voltage electricity, radiation or
electromagnetic fields, lasers, noise > 80dB TWA, Allergens/Biohazards/Chemicals
/Asbestos, confined spaces, working at heights ?10 feet, temperature extremes,
heavy metals, unusual work hours or routine overtime and/or inclement weather.